Predisposition of Dog Breeds to Disease

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E

English Bulldog

• Atopy
• Chemodectoma +/- pericardial effusion
• Cleft palate
• Constipation
• Demodicosis
• Facial fold intertrigo
• Fecal incontinance
• Folliculitis and pedal furunculosis, bacterial
• Follicular dysplasia (flank)
• Hypothyroidism
• Malassezia dermatitis
• Mitral vlave dysplacia
• Muzzle furunculosis, bacterial
• Perisstant right aortic arch
• Pulmonic stenosis
• Sterile pyogranuloma syndrome
• Subaortic stenosis
• Tail fold intertrigo
• Tetralogy fo Fallot
• Vascular compression of the esophagus
• Ventricular septal defect

English Cocker Spaniel

• Cataracts
• Cryptorchidism
• Deafness
• Food hypersensitivity

  Generalized progressive retinal atrophy

  • Attenuation of retinal vessels
  • Increased reflectivity of tapetum lucidum affecting young dogs
  • Characterized by night blindness
  • Progressing to blindness
• Glaucoma
• Hemophilia A
• Hypothyroidism
• Juvenile amaurotic idiocy
• Lip fold intertrigo
• Malasezia dermatitis
• Otitis externa
• Pseudohermaphroditism
• Seborrhea, primary
• "Swimmers"
  • Characterized by inability to stand at 4-6 weeks of age.

English Foxhound

• Deafness
  • Cochlear degeneration
• Osteochondrosis of the spine
  • Anterio-posterior herniation of the intervertebral end plate into the vertebral body
  • stiff gait prevents proper galloping
  • Occurs from 7-10 months of age.

English Setter

• Anaphylactic reaction to routine immunization
• Carcinoma and lymphosarcoma of oral and nasal cavity
• Cataract
• Craniomandibular osteoarthropathy
• Deafness
• Eclampsia
• Ectropion
  • Outward rolling eyelids
• Entropion
  • Inward rolling eyelids
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF and Factor VIII
• Hip dysplasia
  • Deformed coxofemoral joints with clinical signs of none to severe hip lameness
  • Radiographically there may be shallow acetabulum, flattened femoral head, subluxation, and/or secondary degenerative joint disease.
• Hypoglycemia
  • Concentration of glucose in the blood below the normal limit.
• Progressive retinal atrophy
• Prolonged anesthesia
• Pyoderma
• Recessive juvenile amaurotic idiocy
  • Dullness and reduced vision at around 12-15 months of age.
  • Developing into muscle spasms at 18 months, becoming seizures.

English Sheepdog

• Dilated cardiomyopathy

English Springer Spaniel

• Central progressive retinal atrophy
  • Mottling and increased reflectivity of area centralis
  • Resulting in loss of central vision
  • Affecting dogs 3-5 years of age
  • Difficulty in seeing stationary objects 
  • Sight is best in dim light.
• Cleft palate
  • Median fissures due to nonclosure of bones
  • Environmental and/or genetic factors may be involved.
• Congenital Femoral Shift
• Congenital seborrhea
• Cutaneous asthenia (Ehlers-Danlos Syndrome)
  • Connective tissue abnormality
  • Fragile, lax skin
  • Hyperextensibility of joints
• Diabetes mellitus
  • Inability to oxidize carbohydrates due to faulty pancreatic activity
  • Results in hyperglycemia
  • Symptoms of thirst, hunger, emaciation and weakness
• Dilated cardiomyopathy
• Distichiasis
  • An abnormal  row of eyelashes
• Ectropion
  • Outward rolling eyelids
• Entropion
  • Inward rolling eyelids
• Epilepsy
• Episodic collapse
• Factor XI (PTA) deficiency
• Food hypersensitivity
• Fucosidosis
• Glaucoma
• Hanging tongue
• Hip dysplasia
  • Deformed coxofemoral joints
  • Clinical signs from none to severe hip lameness
  • Radiographically there may be shallow acetabulum, flattened femoral head, subluxation and secondary degenerative joint disease
• Hypothyroidism
• Idiopathic onychodystrophy
• Lip fold intertrigo
• Malasezia dermatitis
• Myasthenia gravis
• Otitis externa
• Patent ductus arteriosus
• Patellar luxation
  • Medial/lateral
  • Most common are medial
  • Tibial rotation on the long axis
  • Bending of the distal end of the femoral shaft
  • Shallow femoral trochlea
  • Lameness at 4-6 months of age
• Persistent atrial standstill
• Phosphofructokinase deficiency
  • Enzyme deficiency
  • Diseased red blood cells and muscle cells
  • Intermittent dark urine after strenuous exercise
• Persistent pupillary membrane 
• Primary retinal dystrophy
• Progressive retinal degeneration type II
  • Central retinal atroph
• Psoriasiform-lichenoid dermatosis
• Retinal dysplasia
• Seborrhea, primary
• Umbilical hernia
• Ventricular septal defect

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F

Field Spaniel

• Anesthetic sensitivity
• Hip dysplasia
• Hypothyroidism
• Pyometra

Finnish Spitz

• Adult onset epilepsy
• Cleft palate
• Ectasia
• Luxated patella
• Pemphigus foliaceous

Flat Coated Retriever

• Diabetes insipidus
• Epilepsy
• Glaucoma
• Hip dysplasia
• Histiosarcoma
• Luxating patella
• Megaesophagus

Fox Terrier

• Ataxia
• Atopic dermatitis
• Cataract
• Circumanal neoplasia
• Colonic disease
• Corneal dystrophy
  • Both epithelial(superficial) and endothelial(seen in Wire-haired Terriers)
• Deafness
• Degenerative valve disease
• Dislocation of the shoulder
• Distichiasis
• Ectopic ureter (familial relationship)
• Esophageal achalasia
• Glaucoma
• Goiter
• Juvenile cataract
• Legg-Perthes disease
• Lens luxation
• Persistent aortic arch
  • Development from right aortic arch instead of left
  • Crosses the esophagus forming a ring with the pulmonary artery and the ligamentum arteriosum
  • Produces esophageal stenosis
• Pulmonic stenosis
  • Narrow pulmonary artery at its origin
• Recessive oligodontia
• Secondary glaucoma
  • Subluxation of the lens
• Superficial corneal erosion (seen in Wire-haired Terriers)
• Tetralogy of Fallot (Wirehaired)
• Trichiasis (in Toy)

French Bulldog

• Brachury
  • Short tail
• Cleft palate and lip
  • Median fissures due to non-closure of bones
• Elongated soft palate
• Hemivertebra
  • Asymmetric abnormal development of vertebrae which may result in neonatal death or cord compression in older puppies
  • Affected vertebrae become wedge-shaped due to underdevelopment of one half 
  • Results in scoliosis or kinked tails and crowding of ribs if present in the thoracic area
• HemophiliaA, Factor VIII, or AHF deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF and Factor VIII
• Hemophilia B, Factor IX deficiency
  • Prolonged bleeding
  • Abnormal prothrombin consumption and thromboplastin generation
  • Decreased factor IX
  • Heterozygotes with hemophilia B bleed more than heterozygotes with hemophilia A

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G

German Shepherd Dog

• Atopic dermatitis
• Axonopathy
• Bacterial overgrowth (GI tract)
• Behavioral abnormalities
• Bilateral cataract
  • Opaque lenses
• Calcinosis circumscripta tongue
• Cellulitis
  • Folliculitis and furunculosis, bacterial
• Cleft of lip and palate
  • Medial fissures due to nonclosure of bones
  • Environmental and/or genetic factors may be involved.
• Collagen disorder of footpads
• Conjunctival dermoid cyst
• Contact hypersensitivity
• Cystinuria
  • Excess cystine in the urine
  • Predisposing to calculi.
• Deafness
• Dilated cardiomyopathy
• Discoid lupus erythematosus
• Ectasia syndrome
• Elbow dysplasia
• Enostenosis (Eosinophilic panostitis)
  • Limb pain and intermittent lameness between the ages of 6 and 12 months
  • Signs are persistent for two months
  • Subsequent recovery.
• Epilepsy
  • EEG may detect at an early age
• Esophageal achalasia
• Exocrine pancreatic insufficiency
• Eversion of nictitating membrane
• Fibrous subaortic stenosis
  • Narrow aorta below its valve
• Flea bite hypersensitivity
• Fly dermatitis of ear tips
• Food hypersensitivity
• Gastroenteritis
• Hemophilia A, Factor VIII, or AHF deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT, reduced AHF and Factor VIII
• Hepatic angiosarcoma
• Hip dysplasia
  • Deformed coxofemoral joint
  • Clinical signs ranging from none to severe hip lameness
  • Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation and/or secondary degenerative joint disease.
• Hypothyroidism
• Infective endocarditis
• Inflammation of the third eyelid
• Inflammatory bowel disease
• INherited ventricular arrhythmias
• Insect or arachnid-related eosinophilic furunculosis (face)
• Lupoid onychodystrophy
• Megaesophagus
• Mitral valve dysplasia
• Mucocutaneous bacterial pyoderma
• Nasal furunculosis, bacterial
• Nodular dermatofibrosis with renal cystadenocarcinoma
• Oropharyngeal neoplasia
• Osteochondritis dissecans
• Osteosarcoma
• Otitis externa
• Palpebral dermoid
• Pancreatic insufficiency
• Pannus
• Patent ductus arteriosus
• Pemphigus erythematosus
• Perianal fistula
• Persistent right aortic arch
  • Aortic development from right fourth aortic arch instead of left crosses the esophagus forming a ring around it with the pulmonary artery and the ligamentum arteriosum.
  • Produces esophageal stenosis.
• Phimosis
• Pituitary dwarfism
• Progressive posterior paralysis
  • Occurs in middle age to older dogs
  • Some predilection for males
  • Gradual onset
  • Asymmetric in rear limbs
• Pyotraumatic dermatitis
• Renal cortical hypoplasia
  • Polydipsia
  • Polyuria
• Right atrial hemangiosarcoma +/- pericardial effusion
• Seborrhea, primary
• Senile cataract
• Sialocele
• Silica uroliths
• Stress induced diarrhea
• Subaortic stenosis
• Systemic lupus erythematosus
• Tarsal fistulae
• Tricuspid vlave dysplasia
• Uberreiter's syndrome
  • Degenerative pannus
  • Chronic superficial keratitis
• Uterine leiomyomas
• Vascular anomaly with compression of the esophagus
• Vitiligo
• Von Willebrand's disease; pseodohemophilia; vascular hemophilia
  • Prolonged bleeding time.
  • Low factor VIII
  • Reduced platelet adhesiveness and abnormal prothrombin consumption time.
  • May exhibit recurrent melena
  • Prolonged estrual bleeding
  • Excessive bleeding after trauma
  • subcutaneous hematomas

German Shorthaired Pointer

• Amaurotic idiocy
  • CNS storage disease
  • Characterized at 6 months of age by nervousness and decreased training ability
  • At 9-12 months progressive ataxia and impaired vision
• Corneal dystrophy
• Entropion
  • Inward rolling eyelids
• Eversion of nictating membrane
• Fibrosarcoma
• Lymphedema
  • Nonpainful pitting edema
  • Most commonly seen in the hind legs and in severe cases the entire body.
  • Moderately affected animals gradually lose edema by 3 months of age
  • Popliteal lymph nodes are absent or hypoplastic
• Malocclusion
• Melanoma
• Oropharyngeal neoplasia
• Pseudohermaphroditism
• Strabismus
• Subaortic stenosis
• Thrombocytopathy, platelet function defect
  • Moderate to severe bleeding diathesis
  • Glanzmann's disease
• Subaortic stenosis
  • Narrow aorta below its valve

German Wirehaired Pointer

• Malocclusion
• Subcutaneous cysts

Giant Schnauzer

• High incidence of hip dysplasia
• Hypothyroidism
• Malabsorption of cobalmin
• Osteochondritis dissecans
• Seborrhea
• Von Willebrand's disease

Golden Retriever

• Acute moist dermatitis
• Acral lick dermatitis
• Atopy
• Bilateral cataract
  • Opaque lenses
• Canine X-linked muscular dystrophy
• Cataract with microphthalmia
  • Opaque lenses with small eyes
  • Associated with retinal folds
• Central progressive retinal atrophy
  • Mottling and increased reflectivity of area centralis
  • Resulting in loss of central vision.
  • Difficulty in seeing stationary objects
  • Sight is best in dim light
  • Affecting dogs 3-5 years of age
• Central retinal degeneration
• Cerebellar hypoplasia
• Diaphragmatic hernia
• Distichiasis
  • An abnormal row of lashes
• Elbow dysplasia
• Elbow osteochondrosis
• Entropion
• Folliculitis and furunculosis, bacterial
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding 
  • Hemorrhagic episodes
  • Prolonged PTT, reduced AHF and Factor VIII
• Hip dysplasia
• Hypothyroidism
• Inhalant allergies
• Juvenile cellulitis
• Mitral vlave dysplasia
• Muscular dystrophy
• Nasal hypopigmentation
• Oropharyngeal neoplasia
• Osteosarcoma
• Pericardial effusion - idiopathic
• Pyotraumatic dermatitis
• Pyotraumatic folliculitis and furunculosis, bacterial
• Retinal dysplasia
• Right atrial hemangiosarcoma +/- pericardial effusion
• Sterile pyogranuloma syndrome
• Subvalvular aortic stenosis
• Taurine deficient familial Dilated cardiomyopathy
• Tricuspid valve dysplasia
• Von Willebrand's disease; pseudohemophilia; vascular hemophilia
  • Prolonged bleeding time
  • Low Factor VIII
  • Reduced platelet adhesiveness and abnormal prothrombin consumption time.
  • May exhibit recurrent melena
  • Prolonged estrual bleeding
  • Excessive bleeding after trauma
  • Subcutaneous hematomas

Gordon Setter

• Atopy
• Cerebellar cortical abiotrophy
• Entropion
• Generalized progressive retinal atrophy
  • Attenuation of retinal vessels
  • Increased reflectivity of tapetum lucidum
  • Affecting young dogs
  • Characterized initially by night blindness
  • Progressing to blindness
• Hip dysplasia
  • Deformed coxofemoral joints 
  • Clinical signs from none to severe hip lameness.
  • Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation, and secondary degenerative joint disease.
• Hypothyroidism
• Juvenile cellulitis
• Progressive retinal degeneration

Great Dane

• Acral furunculosis, bacterial
• Acral lick dermatitis
• Atopy
• Cervical calcinosis circumscripta
• Cerebellar hypoplasia
• Cystinuria
  • Excess cystine in the urine
  • Predisposing to calculi.
• Deafness
  • Seen in homozygous merles in conjunction with ocular defects.
• Dilated Cardiomyopathy -- x linked
• Elbow dysplasia
• Eversion of the nictitating membrane
• Folliculitis and furunculosis, bacterial
• Gastric dilitation-volvulus
• Heterochromia iridis
  • "Walleye"
  • Blue and white iris
• Hypothyroidism
• Lone atrial fibrillation
• Megaesophagus
• Metabolic bone disease
• Microphthalmia
  • Small eyes
  • Result of merle to merle mating 
  • Seen in homozygous merles
• Mitral valve dysplasia
• Muzzle furunculosis, bacterial
• Necrotizing myelopathy
  • Acute atraumatic, flaccid paralysis of the front limbs
• Osteochondritis dissecans
  • Saucer shaped necrosis or flap in the posterior central portion of humeral head
  • Causes very distinct favoring of affected limb
• Osteosarcoma
• Pedal furunculosis, bacterial
• Persistant right aortic arch
• Progressive ataxia
• Pulmonic stenosis
• Retinal dysplasia (Harlequin)
• Solar dermatosis (Harlequin)
• Spondylolisthesis
  • "Wobbler syndrome"
  • Anterior ventral canal is narrower than the posterior canal in the dorsoventral direction between C3 and C7
• Stockard's paralysis
  • Preganglionic sympathetic degeneration
  • Onset at about 3 months of age
• Subaortic stenosis
• Tricuspid valve dysplasia

Great Pyrenees

• Achondroplasia
• Anophthalmia
  • Missing eyeballs
• Blue eyes
• Brittle bone syndrome
• Cataracts
• Cleft palate
• Cryptorchidism
• Deafness
• Defective heart
• Demodicosis
• Entropion
  • Inward rolling lids
• Factor IX(PTA) deficiency
• Hip dysplasia
  • Deformed coxofemoral joints
  • Clinical signs from none to severs hip lameness
  • Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation, and/or secondary degenerative joint disease
• Malocclusion
• Missing dewclaws
• Monorchidism
• Persistent hyaloid artery
• Pyotraumatic dermatitis
• Slipped patella
• Tricuspid valve dysplasia

Greyhound

• Anesthetic risk
• Azoturia-like disease
  • Excessive nitrogen compounds in the urine
• Bloat
• Cheyletiellosis
• Esophageal achalasia
• Hemophilia A, Factor VII or AHF deficiency
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF and Factor VIII
• Lens luxation
• Megaesophagus
• Persistent pupillary membrane
• Persistent right aortic arch
• Predisposition to dystocia
  • Anatomical peculiarities 
  • Fetal death
  • Over nervousness of the dam
• Retinal dystrophy
• Short spine
• Von Willebrand's disease

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H

Harrier

• Hip dysplasia
• Malocclusion

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I

Ibizan Hound

• Allergic reaction to several chemicals
• Anesthesia risk
• Bloat
• Deafness
• Seizures
• Unilateral cryptorchidism

Irish Setter

• Acral furunculosis, bacterial
• Acral lick dermatitis
• Atopy
• Carpal luxation
• Cataract , juvenile cataract
• Color dilution alopecia
• Constipation
• Corneal dystrophy
• Deformed tail
• Dilated cardiomyopathy
• Distichiasis
• Enlarged orbit
• Entropion
  • In rolling eyelids
• Fecal incontinence
• Folliculitis and furunculosis, bacterial
• Generalized myopathy
  • Stiff gait
  • Swallowing difficulty
  • Enlarged tongue
  • Atrophic muscles
  • First seen at 8 weeks of age
  • Serum Creatine phosphokinase and aldolase levels are high
• Generalized progressive retinal atrophy
  • Attenuation of retinal vessels
  • Increased reflectivity of tapetum lucidum 
  • Affecting young dogs 
  • Characterized initially by night blindness and progressing to blindness
• Granulocytopathy
  • Increased susceptibility to infection
  • Fever gingivitis
  • Destruction of bone in mandibles, radius and ulna
• Hemophilia A,Factor VIII deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes 
  • Prolonged PTT
  • Reduced Factor VIII
• Hip dysplasia
• Hypothyroidism
• Idiopathic epilepsy
• Inhalant allergies
• Megaesophagus
• Metabolic bone disease
• Osteochondritis dissecans
  • Inflammation, both bone and cartilage
  • Results in splitting of cartilage into the joint
  • Especially the knee and shoulder
• Osteosarcoma
• Persistent right aortic arch
  • Aortic development from right fourth aortic arch instead of left and crosses the esophagus
  • Forms a ring around the arch with the pulmonary artery and the ligamentum arteriosum
  • Produces esophageal stenosis
• Persistent pupillary membrane
• Primary megaesophagus
• Progressive retinal degeneration type I (rod-cone dysplasia)
• Quadriplegia with amblyopia
  • Progressive
  • Initially as swimmers at 3 days of age
  • Later inability to stand and dim vision
  • May be accompanied by tremor and nystagmus
• Right atrial hemangiosarcoma +/- pericardial effusion
• Seborrhea, primary
• Uredecrinatological syndrome
• Vascular anomaly with compression of the esophagus
• Wheat-sensitive enteropathy

Irish Terrier

• Cystinuria
  • Excess cystine in the urine
  • Predisposing to calculi
• Hereditary footpad keratosis
• Hereditary myopathy
• Muscular dystrophy
• Tubular transport dysfunction

Irish Water Spaniel

• Hip dysplasia
  • Deformed coxofemoral joints 
  • Clinical signs from none to severe hip lameness
  • Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation, and/or secondary degenerative joint disease.
• Hypotrichosis
• Idiopathic onychodystrophy
• Malocclusion

Irish Wolfhound

• Cataracts
• Dilated Cartiomyopathy
• Heart disease
• Hip and elbow dysplasia
• Hygroma of elbow
• Intrahepatic portosystemic shunts
• Lone atrial fibrillation
• Osteosarcoma
• Progressive retinal atrophy
• Rhinitis syndrome
  • Inflammation of mucous membrane of the nose
• Tail injury

Italian Greyhound

• Epilepsy
• Increased anesthetic risk
• Progressive Retinal Atrophy
• Patellar Luxation
• Vitreous Degeneration
• von Willebrand's disease
• Immune mediated thrombocytopenia
• Monorchidism
• Persistent right aortic arch
  • Aortic development from right fourth aortic arch instead of left.
  • Crosses the esophagus, forming a ring around it with the pulmonary artery and the ligamentum arteriosum.
  • Produces esophageal stenosis.

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J

Jack Russel Terrier

• Deafness
• Demodicosis
• Dermatophytosis
  • Trichophyton mentagrophytes, var. erimacei
• Hereditary ataxia
• Legg perthes
• Luxating patella
• Salivary gland necrosis

Japanese Chin

• Achondroplasia
• Monorchidism

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K

Keeshond

• Aberrant cilia
• Conotrunctal Defects (CTD)
  • A series of genetically relaed congenital cardiac malformations that include conal septum, conal Ventricular septal defect, Tetralogy of Fallot, and persistant truncus arteriosus
• Ectopic cilia
• Epilepsy
  • Usually seen at 3 years of age
  • EEG may detect at an earlier age
• Hypogonadism of intact male
• Hyposomatotropism
• Hypothyroidism
  • Deficient thyroid activity
• Mitral valve dysplasia
• Patent ductus arteriosus
• Predisposition of melanoma
• Primary hyperparathyroidism
• Pulmonic stenosis
• Renal cortical hypoplasia
• Sebaceous cyst
• Tetralogy of Fallot
  • Ventricular septal defect
  • Pulmonary stenosis
  • Dextroposition of the aorta
  • Right ventricular hypertrophy

Kerry Blue Terrier

• Cerebellar cortical and extrapyramidal nuclear abiotrophy
  • Onset 9-16 weeks
  • Pelvic limb stiffness
  • Mild head tremor
  • Progressing to paralysis
• Distichiasis
• Entropion
  • Inward rolling eyelids
• Footpad keratoses (corns)
• Hair follicle tumors
• Keratoconjunctivitis sicca
• Narrow palpebral fissure
• Otitis externa
• Patent ductus arteriosus
• Spiculosis
• Trichiasis (upper lateral cilia)
• Ununited anconeal process

Komondorok

• Cysts
• Entropion
  • Inward rolling eyelids
• Hip dysplasia
  • Deformed coxofemoral joints
  • Clinical signs from none to severe hip lameness
  • Radiographically, there may be shallow acetabulum, flattened femoral head subluxation and secondary degenerative joint disease.
• Skin problems

Kuvasz

• Deafness
• Hip dysplasia
  • Deformed coxofemoral joints
  • Clinical sighs from none to severe hip lameness
  • Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation and secondary joint disease

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L

Labrador Retriever

• Acral furunculosis, bacterial
• Acral lick dermatitis
• Associated occular and skeletal dysplasia
• Atherosclerosis
  • Lethargy
  • Anorexia
  • Welkness
  • Collapse
  • Vomiting
• Atopy
• Bilateral Cataract
  • Opaque lenses
• Canine congenital hypotrichosis
• Carpal subluxation (XR)
  • Bilateral
  • Gene is allelic to the gene for Hemophilia A
• Central progressive retinal atrophy (autosomal recessive)
  • Screening available using the Optigen DNA marker test www.optigen.com
  • Mottling and increased reflectvity of area centralis resulting in loss of central vision
  • Difficulty in seeing stationary objects
  • Sight is best in dim light
  • Affecting dogs 3-5 years of age.
• Central retinal degeneration
• Chronic hepatitis
• Coloboma
• Congenital phimosis and cutaneous mast cell tumors
• Copper toxicosis
• Corneal opacity
• Cortical degeneration
• Craniomandibular osteopathy
  • Irregular osseous proliferation of mandible and tympanic bulla
  • Discomfort from eating
  • Intermittent fever up to 104 deg. F
  • Beginning at age 4-7 months.
• Cystinuria (SLR)
  • Excess cystine in the urine
  • Predisposing to calculi
• Dacrocystitis
• Deficiency of type II muscle fibers
  • Signs include a marked creatinuria and deficiency of muscle mass.
• Diabetes mellitis
  • Inability to oxideze carbohydrates due to faulty pancreatic activity
  • Results in hypoglycemia with symptoms of thirst, hunger, emaciation, and weakness.
• Dilated cardiomyopathy
• Distichiasis
  • Abnormal row of eyelashes
  • Results in irritation and epiphora
• Dwarfism associated with retinal dysplasia
• Elbow osteochrondrosis
• Entropion
  • Inrolling of the eyelids
• Epilepsy
• Factor IX deficiency (congenital)
  • Subcutaneous hematomas
  • Profuse hemorrhage from surgical wound.
• Folliculitis and furunculosis, bacterial
• Food allergy
• Hemophilia A, Factor VIII or AHF deficiency (SLR)
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF and Factor VIII
• Hereditary myopathy
• Hip Dysplasia
  • Deformed coxofemoral joints
  • Clinical sighs from none to hip lameness
  • Radiographically there may be shallow acetabulum, flattened femoral head, subluxation, and secondary degenerative joint disease.
• Hypertrophic osteodystrophy
• Hypoglycemia
  • concentration of glucose in the blood below the normal limit.
• Hypothyroidism
  • Deficient thyroid activity
• Juvenile Cataract
• Leukotrichia
• Liver disease and liver cirrhosis (hereditary factors)
• Megaesophagus
• Melanoma
• Missing teeth
• Muscular dystrophy
  • Generalized muscle atrophy
  • Depressed spinal reflexes
  • "Bunny hopping" gait
• Nyatagmus
• Patent ductus arteriosus
• Pericardial effusion - idiopathic
• Persistent hyaloid artery
• Persistent pupillary membrane
• Postnatal cerebellar
• Prolapsed rectum
• Prolapsed uterus
• Pulmonic stenosis
• Pyotraumatic dermatitis
• Receptor dystrophy
• Retinal detachment
• Retinal dysplasia
• Right atrial hemangiosarcoma +/- pericardial effusion
• Sebborhea, primary
• Shoulder dysplasia
• Shoulder lameness
• Tricuspid valve disease
• Ununited anconeal process
• Waterline disease

Lakeland Terrier

• Cryptorchidism
• Distichiasis
  • Abnormal row of eyelashes
  • Results in irritation and epiphora
• Lens luxation
• Undershot jaw
  • Abnormal relative growth of the mandible
• Ununited anconeal process
• Ventricular septal defect

Lhasa Apso

• Aberrant cilia
• Atopy
• Congenital hypotrichosis
• Corneal ulcers
• Degenerataive valve disease
• Distichiasis
  • Abnormal row of eyelashes
  • Results in irritation and epiphora
• Ectopic cilia
• Entropion (medial)
  • Inward rolling eyelids
• Hip dysplasia
• Inguinal hernia
  • Found in this breed to be high risk.
  • Defective formation of linea alba associated with protrusion of abdominal contents through inguinal canal.
• Inhalant allergies
• Injection reaction
• Keratoconjunctivitis sicca
• Lack of ADH
• Lissencephaly
  • Congenital absence of cerebrocortical convolutions
  • Signs within the first year of life
  • Behavioral, visual and convulsive disorders.
• Malassezia dermatitis
• Patellar luxation
  • Medial or lateral
  • Most common are medial
  • Accompanied by tibial rotation on the long axis
  • Bending of the distal end of the femoral shaft
  • Shallow femoral trochlea
  • Lameness at 4-6 months of age.
• Progressive retinal atrophy
• Renal cortical hupoplasia
  • Proven in this breed to be inherited
  • Bilateral renal cortical hypoplasia leading to uremia and secondary hyperparathyroidism
  • Signs begin at around 1 year of age

Lundenhund

• Protein-losing enteropathy

Return to Index.

M

Maltese

• Aberrant cilia
• Blindness (congenital)
• Cryptorchidism
• Deafness
• Hypertrophic pyloric gastropathy
• Hydrocephalus
• Hypoglycemia
  • Concentration of glucose in the blood below normal limit.
• Malocclusion of misalignment
• Patent ductus arteriosus
• Patellar luxation
  • Medial or lateral
  • Most common are medial
  • Accompanied by tibial rotation on the long axis
  • Bending of the femoral shaft
  • Shallow femoral trochlea
  • Lameness at 4-6 months of age
• Poor pigmentation

Manchester Terrier

• Cutaneous asthenia
• Grand mal epilepsy
• Hypertrophic pyloric gastropathy
• Legg-Perthes disease
  • Avascular necrosis of femoral head
• Secondary glaucoma; luxating lens

Mastiff

• Bloat
• Ectropion
  • Outward rolling eyelids
• Elbow dyslasia
• Mitral valve dysplasia
• Persistent pupillary membranes
• Pulmonic stenosis
• Vaginal hyperplasia

Miniature Pinscher

• Corneal dystrophy
• Degenerative valve disease
• Dislocation of the shoulder
• Entropion
• Inguinal hernia
  • Defective formation of linea alba associated with protrusion of abdominal contents through the inguinal canal.
• Keratoconjunctivitis sicca
• Legg-Perthes disease
  • Avascular necrosis of femoral head
• Progressive retinal atrophy
  • Dilated pupils react sluggishly to stimuli
  • Night blindness progrressing to blindness
  • Atrophy of retinal  vessels
  • Increased reflectivity to tapetum lucidum
• Skin disease- lack of pigment

Miniature Schnauzer

• Atherosclerosis
• Atopy
• Atresia of lacrimal drainage apparatus
• Aurotrichia
• Bilateral cataract
• Corneal dystrophy
• Cryptorchidism
• Degenerative valve disease
• Distichiasis
• Esophageal achalasia
• Food allergy
• Hemorrhagic gastroenteritis
• Hyperlipidemia
• Hypothyroidism
• Inhalant allergy
• Juvenile cataract
• Juvenile renal disease
• Legg-Perthes disease
  • Avascular necrosis of femoral head.
• Megaesophagus
• Microphthalmia
• Muscular dystrophy
• Nephritis
• Pancreatitis
• Patent ductus arteriosus
• Persistent pupillary membrane
• Portosystemic shunts
• Progressive retinal atrophy
• Prone to cystitis and bladder stones
• Pseudohermaphroditism
• Pulmonic stenosis
  • Narrow pulmonary artery at its origin
• Schnauzer comedo syndrome
  • Comedo - from acranial to tail head
• Sertoli cell tumor
• Sick sinus syndrome
• Sinoatrial syncope
• Spinaliomas
• Subcorneal pustular dermatosis
• Von Willebrand's disease
  • "Pseudohemophilia"
  • "Vascular hemophilia"
  • Incomplete autosomal dominant
  • Prolonged bleeding time
  • Low Factor VIII
  • Reduced platelet adhesiveness and abnormal prothrombin consumption time
  • May exhibit recurrent melena
  • Prolonged estrual bleeding 
  • Excessive bleeding after trauma
  • Subcutaneous hematomas

Return to Index.

N

Newfoundland

• Atrial septal defect
• Avulsion fractures
• Bloat
• Dilated Cardiomyopathy 
• Dermoid cyst of the cornea
• Dilated cardiomyopathy
• Ectopic ureter
• Ectropion
  • Outward rolling eyelids
• Elbow dysplasia
• Entropion
  • Inward rolling eyelids
• Eversion of cartilage of the third eyelid.
• Folliculitis and furunculosis, bacterial
• Hip dysplasia
• Hot spots
• Kinked tails
• Megaesophagus
• Mitral valve dysplasia
• Mitral valve stenosis
• Patent ductus arteriosus
  • Persistence and nonclosure of ductus arteriosus between aorta and pulmonary artery with right to left shunt
• Pemphigus foliaceus
• Pulmonic stenosis
• Pyotraumatic dermatitis
• Subvalvular aortic stenosis
  • Narrow aorta below its valve
• Ununited anconeal process
• Ventricular septal defect

Norwegian Elkhound

• Cataracts
• Distichiasis
• Generalized progressive retinal atrophy
  • Attenuation of retinal vessels
  • Increased reflectivity of tapetum lucidum 
  • Affecting young dogs
  • Characterized initially by night blindness
  • Leading to blindness
• Glaucoma (Primary open-angle glaucoma)
• Keratoacanthoma
• Progressive retinal degeneration type I (rod dysplasia)
• Renal Cortical hypoplasia
  • Proven in this breed to be inherited
  • Bilateral renal cortical hypoplasia 
  • Leading to uremia
  • Secondary hyperparathyroidism
  • Signs begin at around 1 year of age
• Seborrhea
• Subcutaneous cysts

Norwich Terrier

• Summer eczema

Return to Index.

O

Old English Sheepdog

• Atopy
• Bilateral cataract
• Bloat
• Cataract (congenital)
• Demodicosis
• Dilated cardiomyopathy
• Distichiasis
• Elongated tongue
• Entropion
• Hip dysplasia
  • Deformed coxofemoral joints with clinical signs from none to severe lameness.
  • Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation , and/or degenerative joint disease.
• Immune mediated hemolytic anemia
• Juvenile cataracts
• Metachondrial myopathy
  • Exercise intolerance
• Pedal furunculosis, bacterial
• Persistent atrial standstill
• Progressive retinal degeneration
• Retinal detachment
• Tricuspid valve disease
• Wobbler's syndrome
  • Spondylolisthesis
  • Anterior ventral canal is narrower than the posterior canal in the dorsal-ventral direction between C3 and C7.

Otter Hound

• Elbow dysplasia
• Hip dysplasia (severe)
  • Deformed coxofemoral joints with clinical signs from none to severe hip lameness.
  • Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation, and/or secondary degenerative joint disease.
• Platelet disorder
  • "Thrombocytopathy with giant platelets"
  • Mild to moderately severe bleeding
  • Prolonged bleeding time
  • Abnormal platelet aggregation  and adhesiveness
  • Poor clot retraction
• Sebaceous cysts

Return to Index.

P

Papillon

• Anasarca
  • Walrus or rubber puppies
• Deafness
• Entropion
• Patellar luxation
  • Medial or lateral, most common are medial
  • Tibial rotation on the long axis
  • Bending of the distal end and shallow femoral trochlea
  • Lameness at 4-6 months of age

Pekinese

• Atypical pannus
• Cheyletiellosis
• Corneal ulceration
• Cryptorchidism
• Degenerative valve disease
• Distichiasis
  • Two rows of eyelashes
  • Results in irritation and epiphora
• Dystocia
• Ectopic cilia
• Elongated soft palate
• Hairy caruncle
• Hypoplasia of dens (Odontoid process)
  • Either hypoplasia of dens or its nonunion with C2 produces atlantoaxial subluxation
  • Onset any age 
  • Producing signs ranging from neck pain to quadriplegia
• Inguinal hernia
  • Defective formation of linea alba associated with protrusion of abdominal contents through inguinal canal.
• Intervertebral disc disease
  • Predisposition possibly due to breed conformation and other factors
• Juvenile cataract
• Lacrimal duct atresia
  • Congenital absence of openings to lacrimal canal
• Microphthalmia
  • Abnormal smallness of eyes
• More prone to urolith formation
• Nasal fold trichiasis
• Persistent penile frenulum
• Pigmentary keratitis
• Progressive retinal atrophy
  • Dilated pupils react sluggishly to stimuli
  • Night blindness progressing to blindness
  • Atrophy of retinal vessels
  • Increased reflectivity of tapetum lucidum
• "Swimmers"
  • Characterized by inability to stand at 4-6 weeks and flattened chest.
• Trichiasis
  • Ingrown eyelashes which irritate corneal conjunctiva
• Umbilical hernia

Pembroke Welsh Corgi

• Cervical disc disease
• Cutaneous asthenia 
  • Ehlers-Danlos syndrome
  • Connective tissue abnormality
  • Fragile, lax skin and hyperextensibility of joints.
• Cystinuria
  • Excess cystine in urine
  • Predisposing to calculi
• Dermoid cyst
• Epilepsy
• Generalized progressive retinal atrophy
  • Attenuation of retinal vessels
  • Increased reflectivity of tapetum lucidum
  • Affecting young dogs
  • Characterized initially by night blindness
  • Progressing to blindness.
• Hip dysplasia
• Von Willebrand's disease

Petit Basset Griffon Vendeen

• Gastrointestinal disorders
• Aseptic Meningitis
• Autoimmune Disorders
• Cushing's Disease
• Elbow Dysplasia
• Hip Dysplasia
• Glaucoma
• Idiopathic Epilepsy
• Inguinal Hernias
• Luxating Patellas
• Malocclusion
• Patent Ductus Arteriosus
• Persistent Pupillary Membranes
• Retinal Dysplasia
• Thyroid Dysfunction (hypothyroidism most commonly seen)
• Umbilical Hernias
• Lymphocytic-plasmocytic gastritis
• Additional known conditions for this breed can be found on a list compiled by Dr. George Padgett at using the link below

    http://www.pbgv.org/Images/PDF/HealthSurvey/GeneticDiseaseChart.pdf

Pointer

• Acral mutilation
• Bilateral cataract
• Bithoracic ectromelia
  • Presence of a scapula only with distal structures absent.
• Calcinosis circumscripta
• Callouses
• Cleft palate
• Colonic disease
• Deafness
• Demodicosis
• Epilepsy
• Entropion
  • Inward rolling eyelids
• Eosinophilic Panostitis
• Esophageal sarcoma
• Follicular dysplasia (flank)
• Hepatic angiosarcoma
• Hereditary lupoid dermatosis
• Hip dysplasia
• Inherited dwarfism
• Neurotropic osteopathy
  • Signs at 3-9 months of age
  • Characterized by toe gnawing
  • Self mutilation
  • low sensitivity in distal limbs
  • Vascular degeneration
  • Demyelination in spinal cord
• Progressive retinal degeneration
• Progressive retinal atrophy
  • Pupils react sluggishly
  • Night blindness progressing to blindness
  • Atrophy of retinal vessels
  • Increased reflectivity of tapetum lucidum.
• Sensory neuropathy
• Umbilical hernia

Pomeranian

• Adrenal sex hormone abnormalities
• Atresia of lacrimal puncta
• Cryptorchidism
• Degenerative valve disease
• Dislocation of the shoulder
• Distichiasis
• Dwarfism and dystocia
• Elephant skin
• Epiphora
• Glycogen storage disease
• Hypersomatotropism
• Hypoplasia of dens (Odontoid process)
  • Either hypoplasia of dens or its non-union with C2 produces atlantoaxial subluxation
  • Onset at any age
  • Producing signs from neck pain to quadriplegia
• Nasolacrimal puncta atresia
• Patella luxation
  • May be medial or lateral
  • Most are medial
  • Tibial rotation on its long axis
  • Bending of the distal end of the femoral shaft
  • Shallow femoral trochlea
  • Lameness at 4-6 months of age
• Patent ductus arteriosus
  • Persistence and nonclosure of ductus arteriosus between aorta and pulmonary artery with left to right shunt.
• Progressive retinal atrophy
  • Pupils react sluggishly
  • Night blindness progressing to blindness
  • Atrophy of retinal vessels
  • Increased reflectivity of tapetum lucidum
• Open fontanelles
• Sick sinus syndrome
• Tracheal collapse
  • Decreased rigidity
  • Elongated elastic membrane and increased circumference of the tracheaa
  • Occurs most commonly in obese dogs with dome-shaped heads, well-developed necks and narrow thoracic inlets
  • Average age of 7 years
  • May be surgically corrected
• Trichiasis

Poodle (miniature- not to exceed 15 inches; Toy not to exceed 10 inches)

• Achondroplasia
  • Impaired ossification of long bone cartilage
  • Producing abnormal short limbs
• Adult onset Growth Hormone deficiency
• Amaurotic idiocy
• Atopic dermatitis
• Atresia of lacrimal puncta and nasolacrimal duct
• Atypical pannus
• Behavioral abnormalities
• Cerebrospinal demyelination
• Chronic superficial keratitis
• Cryptorchidism
• Congenital deafness
• Corneal dystrophy
• Corneal erosion, superficial
• Cushing's syndrome
  • Hyperadrenocorticism
• Cystinuria
• Degenerative valve disease
• Distichiasis
• Ear infections
• Ectodermal defects
  • Symmetrical areas of alopecia (Miniature Poodle)
  • Affects 2/3 of body including head, ventral trunk, dorsal pelvic region and proximal legs.
• Ectopic ureters
• Entropion
  • Inward rolling eyelids
• Epilepsy
  • EEG may detect at an early age
• Epiphora
  • Excessive tearing
• Epiphyseal dysplasia
  • Hindleg joints of puppies sag
  • Puppies move with swaying gait of hindquarters
  • Radiographically, "stippling" from defective ossification of epiphyseal site with several fine foci of bone.
• Glaucoma (primary narrow-angle)
• Hairlessness
• Heart valve incompetence
• Hemeralopia
  • Day blindness
  • Inability to see effectively in bright or direct light.
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF and Factor VIII
• Hemorrhagic gastroenteritis
• Hypoplasia or aplasia of optic nerve
• Hyposomatotropism
• Hypospadia
• Hypothyroidism
• Injection reactions
• Intervetebral disc degeneration
• Iridal atrophy
• Juvenile cataracts
• Lacrimal duct atresia
• Legg-Perthes disease
• Lens-induced uveitis
• Microphthalmia
• Missing teeth
• Narcolepsy
• Neoplasia
• Nonspherocytic hemolytic anemia
• Optic nerve hypoplasia
• Osteogenesis Imperfecta
• Otitis externa
• Overly long hairs on the eyelid skin and cilia (upper lashes)
• Patent ductus arteriosus
• Patellar luxation
  • Medial or lateral
  • Most common are medial
  • Tibial rotation on the long axis
  • Bending of the distal end of the femoral shaft
  • Shallow femoral trochlea
  • Lameness at 4-6 months of age.
• Patent ductus arteriosus
  • "Polygenic threshold trait"
  • Persistence and nonclosure of ductus arteriosus between the aorta and pulmonary artery with left to right shunt.
• Persistent penile frenulum
• Progressive retinal atrophy
  • Pupils react sluggishly
  • Night blindness progressing to blindness
  • Atrophy of retinal vessels
  • Increased reflectivity of tapetum lucidum.
• Progressive rod-cone degeneration
• Pseudohermaphroditism
• Pyruvate Kinase deficiency
• Renal dysplasia (genetic basis)
• Retinal atrophy
• Retinal detachment
• Robertsonian translocation
• Sialocele
• Superficial corneal erosion
• Ventricular septal defect
• Von Willebrand's disease
  • Prolonged bleeding time
  • Low factor VII
  • Reduced platelet adhesiveness
  • Abnormal prothrombin consumption time
  • May exhibit recurrent melena
  • Prolonged estrual bleeding
  • Excessive bleeding after trauma
  • Subcutaneous hematomas

Poodle -Standard ( over 14 inches)

• Addison's Disease -- simple recessive
• Adult onset Growth hormone deficiency
• Alopecia (dilute colors)
• Atopic dermatitis
• Atrial septal defect
• Atypical pannus
• Behavioral abnormalities
• Bloat
• Cataract
• Distichiasis
• Entropion
• Epilepsy
  • EEG may detect at an early age
• Epiphora
  • Excessive tearing
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding time
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF and Factor VIII
• Hip dysplasia
• Hypothyroidism
• Iris atrophy
• Juvenile cataract
• Juvenile Renal disease -- recessive
• Lacrimal duct atresia
• Lobular dissecting hepatitis
• Malignant neoplasm
• Microphthalmia
• Osteogenesis imperfecta
  • Deficient or delayed bone development
  • Results in frequent fractures
  • Appears at 6-8 weeks of age.
• Patent Ductus Arteriosus
• Progressive retinal atrophy
  • Pupils react sluggishly
  • Night blindness progressing to blindness
  • Atrophy of retinal vessels
  • Increased reflectivity of tapetum lucidum
• Sebaceous adenitis
• Squamous cell carcinoma -- Black Standard Poodles
• Ventricular septal defect
• Von Willebrand's disease
  • Pseudohemophilia
  • vascular hemophilia
  • Prolonged bleeding time
  • Low Factor VII
  • Reduced platelet adhesiveness and abnormal prothrombin consumption time
  • May exhibit melena
  • Prolonged estrual bleeding
  • Excessive bleeding after trauma
  • Subcutaneous hematomas

Portugese Water Dog

• Addison's disease
• Cardiomyopathy
• Follicular dysplasia
• Gangliosidosis or G.M.I.
• Hip dysplasia
• INherited juvenile dilated cardiomyopathy
• Progressive retinal atrophy
• Puppy eye syndrome

Pug

• Atopy
• Atrioventricular block
• Atypical pannus formation
• Cleft palate and lips
  • Median fissures due to nonclosure of bones
  • Environmental and/or genetic factors may be involved.
• Corneal dystrophy
• Delayed heat prostration
  • Recurring
• Demodectic mange
• Distichiasis
  • Two rows of eyelashes
  • Results in irritation and epiphora
• Elongated soft palate
• Encephalitis
• Entropion
  • Inward rolling eyelids
• Hairy caruncle
• Hypotrichosis
• Intertrigo
  • Facial fold
  • Tail fold
  • Due to wrinkled head
  • Can become infectious
• Legg-Perthes disease
  • Avascular necrosis of femoral head
• Male pseudohermaphroditism
  • Presence of abdominal testicles, a vulva & an os penis
• Medial luxating patella
• Obesity
• Pigmentary keratitis
• Pinched nostril
• Trichiasis
  • Ingrown eyelashes which irritate corneal conjunctiva
• Urolithiasis

Puli

• Deafness
• Hip dysplasia
  • Deformed coxofemoral joints
  • Clinical signs from none to severe hip lameness
  • Radiographically, there may be shallow acetabuluim, flattened femoral head, subluxation, and/or secondary joint disease.
• Temperament problems

Pyrenean Mountain Dog

• Ectropion
• Entropion
• Persistant pupillary membrane

Return to Index.

Q

Q stuff goes here.

Return to Index.

R

Redbone Coonhound

• Central retinal atrophy

Rhodesian Ridgeback

• Aggression
• Cervical vertebral deformity
• Congenital deafness
• Dermoid sinus
  • Tubular cyst in mid-dorsal line either anterior or posterior to the ridge
  • Due to incomplete separation of skin and spinal cord during development from ectoderm
• Hip dysplasia
  • Deformed coxofemoral joints with clinical signs from none to hip lameness
  • Radiographically, there may be shallow acetabulum
  • Flattened femoral head
  • Subluxation
  • Secondary degenerative joint disease
• HypothyroidismLumbosacral transitional vertebrae

Rottweiler

• Arthrosis of the elbow joint
• Congenital deafness
• Diabetes melitus
• Dilated cardiomyopathy
• Ectropion
  • Outward rolling eyelids
• Elbow dysplasia
• Enlarged orbit
• Entropion
  • Inward rolling eyelids
• Folliculitis and furunculosis, bacterial
• Gastric eosinophilis granuloma
• Hip dysplasia
  • Deformed coxofemoral joints with clinical signs from none to severe hip lameness
  • Radiographically there may be shallow acetabulum
  • Flattened femoral head
  • Secondary degenerative joint disease
• Idiopathic vasculitis
• Kidney failure (familial)
• Lack of traction at the lateral canthus
• Leukoencephalomalacia
• Muscular dystrophy
• Neuroaxonal dystrophy
• Osteochondrosis
  • Hind leg lameness
• Oversized palpebral fissure
• Parvovirus
• Retinal dysplasia
• Subvalvular aortic stenosis
• Vitiligo
  • Asymptomatic depigmentation disease of the skin, mucosa and haircoat

Return to Index.

S

St. Bernard

• Acral lick granuloma
• Acromegaly
• Aphakia with multiple colobomas
  • Absence of lens associated with microphthalmia, acornea, retinal detachment, and anterior synechia
• Cardiomyopathy
• Deafness
• Dermoid cysts of cornea
  • Thick walled cyst containing sebaceous glands, hair follicles and sweat glands
• Diabetes mellitus
• Dilated cardiomyopathy
• Distichiasis
  • Two rows of eyelashes
  • Resulting in irritation and epiphora
• Ectropion
  • Outward rolling eyelids
• Elbow dysplasia
• Entropion
  • Inward rolling eyelids
• Epilepsy
• Epithelial lined cysts of anterior pituitary
• Eversion of nictitating membrane
• Factor I deficiency, fibrinogen deficiency, afibrogenemia, hypo-fibrinogenemia
  • Severe or lethal hemorrhage
• Folliculitis and furunculosis, bacterial
• Gastric torsion
• Genu valgum
  • Knees bowed medially due to rapid growth
  • Prevalent in giant breeds
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF and Factor VIII
• Hemophilia B , Factor IX deficiency
  • Prolonged bleeding
  • Abnormal prothrombin consumption and thromboplastin generation
  • Reduced factor IX
  • Heterozygotes with Hemophilia B bleed more than heterozygotes with Hemophilia A
• Hepato arteriovenous fistula
• Hip Dysplasia
  • Deformed coxofemoral joints with clinical signs from none to severe hip lameness
  • Radiographically there may be shallow acetabulum
  • Flattened femoral head
  • Subluxation 
  • Secondary degenerative joint diseas
• Hypertrophic osteopathy
• Hygroma
• Idiopathic degenerative joint disease
• Lip fold pyoderma
  • Localized
  • Infectious
• Lymphoma
• Metabolic bone disease
• Osteochondrosis dissecans
• Osteosarcoma
• Oversized palpebral  fissure
• Pyotraumatic dermatitis (hot spots)
• Redundant facial skin
• Retained cartilage of distal ulna
• Spleen torsion
• Stockard's paralysis
• Uveodermatologic syndrome

Saluki

• Black hair follicle dysplasia
• Glaucoma
• Persistent pupillary membrane
• Progressive retinal atrophy
• Progressive retinal degereration
• Retinal detachment
• Sensitive to barbiturates

Samoyed

• Atrial septal defects
• Diabetes mellitus
• Dwarfism
  • Radiographic evidence of retarded growth apparent by 12 weeks of age
• Dysplasia of pectinate ligaments
• Glaucoma
• Growth hormone responsive dermatitis
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding 
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF and Factor VIII
• Hereditary nephritis
  • X-linked
• Hip dysplasia
  • Deformed coxofemoral joints with clinical signs from none to severe hip lameness
  • Radiographically there may be shallow acetabulum
  • Flattened femoral head
  • Subluxation
  • Degenerative joint disease
• Muscular dystrophy
  • X-linked
• Persistent pupillary membrane
• Progressive retinal degeneration
• Pulmonic stenosis
• Retinal detachment
• Sebaceous cysts
• Subarotic stenosis
• Uveodermatological syndrome

Schipperke

• Dermatitis
• Entropion
  • Inward rolling eyelids
• Hay fever /asthma
• Hypothyroidism
• Legg-Perthes disease
  • Avascular necrosis of the femoral head
• Narrow palpebral fissure
• Mucopolysaccharidosis Type IIIB -- Test available through the University of Pennsylvania
• Pemphigus foliaceous

Scottish Deerhound

• Dilated Cartiomyopathy -- genetic basis not established
• Gastric torsion
• Osteochondrosis dissecans 
• Osteosarcoma -- autosomal recessive
• Porto systemic liver shunt -- genetic basis not established
• Torsion of the lung
• Torsion of the spleen

Scottish Terrier

• Achondroplasia
  • Imperfect ossification within the cartillage of long bones
  • Producing dwarfism
• Alexander's disease
  • Progressive tetraparesis
• Atopic dermatitis
• Bladder cancer
• Canine lymphoma
• Chronic hepatitis
• Craniomandibular osteopathy
• Cystinuria
  • Excess cystine in the urind
  • Predisposing to calculi
• Deafness
• Ear hematoma
• Elbow dysplasia
• Folliculitis and furunculosis, bacterial
• Hereditary nasal pyogranuloma and vasculitis
• Histiocytoma
• Intervertebral disc disease
• Luxation of the lens
• Melanoma
• Primary uterine inertia
• Pulmonic stenosis
• Pyogranulomatous and vasculitic disorder of nasal planum
• Pyometra
• Scottie cramp
  • Recessive
  • Hyperkinetic disorder characterized by seemingly painless rigidity of limbs, back and tail muscle
  • Both sexes are affected
  • The head may be drawn between the front legs
  • dog recovers in 15-30 seconds
  • Oral Diazapam in doses of 0.5mg/kg given three times daily is highly effective in controlling episodes
• Splayleg
  • Motor disorder
• Thyroid problem
• Urinary calculi
• Von Willebrand's disease, pseudohemophilia, vascular hemophilia
  • Dominant
  • Prolonged bleeding time
  • Low Factor VII
  • Reduced platelet adhesiveness
  • Abnormal prothrombin consumption time
  • May exhibit recurrent melena
  • Prolonged estrual bleeding
  • Excessive bleeding after trauma
  • Subcutaneous hematomas

Sealyham Terrier

• Atopic dermatitis
• Atresia of the nasolacrimal duct
• Cataract
• Deafness
• Lens luxation
  • Results in secondary glaucoma
• Retinal dysplasia
  • Recessive
  • Jumbled, abnormally formed layers of the retina
  • Retinal detachment
  • Blindness
• Secondary glaucoma

Shar-Pei -- see Chinese Sharpei

Shetland Sheepdog

• Achondroplasia
  • Dwarfism
• Bladder cancer
• Bilateral renal agenesis
• Cataract
  • Autosomal recessive
• Central progressive retinal atrophy
  • Mottling and increased reflectivity of area centralis
  • Results in lack of central vision
  • Affects dogs starting at 3-5 years of age
  • Difficulty in seeing stationary objects
  • Sight best in dim light
• Choroidal hypoplasia
• Collie eye anomaly
• Coloboma
• Corneal dystrophy
• Deafness
• Degenerative valve disease
• Dermatomyositis
• Discoid lupus erythematosus
• Distichiasis
• Ectasia syndrome
  • Recessive
  • Excessive tortuosity of retinal vessels
  • Choroio-retinal dysplasia
  • Excavation of the optic disc
  • Retinal detachment
  • Intraocular hemorrhage
  • Veriform streaks of the fundus in young dogs
• Ectopic cilia
• Epidermolysis bullosa
  • Onset at 2-4 months of age
  • Alopecia
  • Erythema
  • Scaling erosions
  • Crusting
  • Sometimes intact vesicle
• Familial dermatitis
• Folliculitis, bacterial
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF
  • Reduced Factor VIII
• Heterochromia iridis
  • "Walleye"
  • Blue and white iris
• Hip dysplasia
  • Polygenic inheritance
  • Deformed coxofemoral joints with clinical signs ranging from none to hip lameness
  • Shallow acetabulum
  • Flattened femoral head
  • Subluxation
  • Secondary degenerative joint disease
• Hypothyroidism
• Idiopathic ulcerative dermatosis
• Muscular dystrophy
• Nasal solar dermatitis
  • Hereditary susceptibility and lack of skin pigment predispose to the disease
• Patent ductus arteriosus
  • Persistence and nonclosure of ductus arteriosus between the aorta and pulmonary artery
  • Right to left shunt
• Personal Pupillary membrane
• Systemic lupus erythematosus
• Ulcer conditions of apocrine glands
• Uveodermatological syndrome
• Von Willebrand's disease
• Yeast dermatitis

Shiba Inu

• Luxated patellas
• Reflex regurgitation
• Uveodermatological syndrome

Shih Tzu

• Achondroplasia
• Atopy
• Chronic keratitis
• Clefts of lip and palate
  • Median fissures due to nonclosure of bones
  • Environmental and/or genetic factors may be involved
• Corneal ulcers
• Degenerative valve disease
• Dermoids
• Entropion
  • Inward rolling eyelids
• Hypospadia
• Hypertrophic pyloric gastrophy
• Inhalant allergies
• Progressive retinal atrophy
• Renal-cortical hypoplasia
  • Bilateral renal cortical hypoplasia leading to uremia and secondary hyperparathyroidism
  • Signs begin at about 1 year of age
• Renal dysplasia
• Retinal detachment
• Trichiasis
• Ventricular septal defect
• Vitriol syneresis
• Von Willebrand's disease
  • Prolonged bleeding time
  • Low Factor VII
  • Reduced platelet adhesiveness 
  • Abnormal prothrombin consumption time
  • May exhibit recurrent melena
  • Prolonged estrual bleeding
  • Excessive bleeding after trauma
  • subcutaneous hematomas

Siberian Husky

• Cataracts
• Congenital laryngeal paralysis
• Corneal dystrophy
• Discoid lupus erythematosus
• Distichiasis
• Ectopic ureter
• Eosinophilic granuloma
• Epilepsy
• Follicular dysplasia
• Hemophilia A
• Heterochromia iridis
• Hip dysplasia
• Hypogonadism in intact male
• Idiopathic onychodystrophy
• Lipidosis
• Oral eosinophilic granuloma
• Persistant pupillary membrane
• Progressive retinal atrophy
  • Dilated pupils react sluggishly
  • Night blindness
  • Progresses to blindness
  • Atrophy of retinal vessels 
  • Increased reflectivity of tapetum lucidum
• Uveitis
• Ventricular septal defect
• Von Willebrand's disease, pseudohemophilia, vascular hemophilia
  • Prolonged bleeding time
  • Low Factor VII
  • Reduced platelet adhesiveness
  • Abnormal prothrombin consumption time
  • Recurrent melena
  • Prolonged estrual bleeding
  • Excessive bleeding after trauma
  • Subcutaneous hematomas
• Zinc responsive dermatosis

Silky Terrier

• Color dilutant alopecia
• Congenital cardiovascular abnromalities
• Cryptorchidism
• Diabetes mellitus
• Hydrocephalus
• Legg-Perthes disease
  • Avascular necrosis of the femoral head
• Occipital dysplasia
• Odontoid process dysplasia
• Patellar luxation
  • Medial or lateral
  • Most common are medial
  • Tibial rotation on the long axis
  • Bending at the distal end of the femoral shaft
  • Shallow femoral trochlea
  • lameness at 4-6 months
• Storage disease
• Tracheal collapse
• Yeast dermatitis

Skye Terrier

• Allergies
• Autosomal thyroid disease
• Congenital kink tail
• Copper-associated hepatopathy
• Enlarged foramen magnum
• Hypoplasia of the larynx
• Juvenile limp
• Megaesophagus
• Premature closure of the distal radius
• Skye hepatitis
• Ulcerative colitis

Soft-Coated Wheaten Terrier

• Cataracts
• Dermatitis
  • Sensitive to grass and fleas
• Heart disease
• Hereditary neuropathy
• Progressive retinal atrophy
• Renal dysplasia

Spinoni Italiani

• Hip dysplasia
• Thyroid imbalance
• Vaginal prolapse

Staffordshire Bull Terrier

• Bilateral cataract
  • Opaque lenses
• Clefts of lip and palate
  • Median fissures due to nonclosure of bones
  • Environmental and/or genetic factors may be involved
• Juvenile cataract
• Primary vitreus

Standard Schnauzer

• Atresia of nasolacrimal puncta
• Benign fatty tumors
• Cataract
• Conjunctivitis
• Follicular dermatitis
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF 
  • Reduced Factor VIII
• Hip dysplasia
• Hypothyroidism
• Narrow palpebral fissure
• Perianal adenomas
  • Occurs in older dogs
• Pulmonic stenosis

Sussex Spaniel

• Heart murmurs / enlarged hearts
• Intervetebral disc disease

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T

Tibetan Spaniel

• lems luxationOxalate nephropathy
• Persistent pupillary membrane
• Progressive retinal atrophy

Toy Terrier

• Lens luxation

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U

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V

Vizsla

• Cataract
• Craniomandibular osteopathy
• Demodicosis
• Entropion
• Facial nerve paralysis
• Factor I defficiency
• Hemangiosarcoma
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding 
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF
  • Reduced Factor VIII
• Hip Dysplasia
• Hyperpigmentation
• Idiopathic Epilepsy -- possibly autosomal recessive
• Lymphoma
• Osteochondritis Dissecans
• Osteochondrosis
• Progressive Retinal Atrophy
• Sebaceous adenitis
• Spinal Dysraphism
• Sterile Pyogranuloma Syndrome
• Syringomyelia
• Umbilical Hernia
• Vasculitis

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W

Weimaraner

• Bloat
• Cutaneous mast cell tumor
• Cryptorchidism
• Dermoid cyst of cornea
• Distichiasis
• Double eyelashes
• Dwarfism
• Enlarged your 
• Entropion
• Eversion of nictitating membrane
• Fibrosarcoma
• Hemophilia A, Factor VIII or AHF deficiency
  • Prolonged bleeding
  • Hemorrhagic episodes
  • Prolonged PTT
  • Reduced AHF
  • Reduced Factor VIII
• Hip dysplasia
• Hypertropic Osteodystrophy
• Myasthenia gravis
• Oropharyngeal neoplasia
• Peritoneopericardial diaphragmatic hernia
• Spinal dysraphism
  • Begins at 4-6 weeks of age
  • Not progressive
  • Crouching stance
  • Abduction of one leg
  • Hopping gait
  • Abnormal proprioception in hindlegs
• Sterile pyogranuloma syndrome
• Tricuspid valve disease
• Umbilical hernia
• Undershot jaw
  • Abnormal growth of mandible
• Ununited anconeal process

Welsh Corgi

• Central retinal atrophy
• Superficial corneal erosion
• Persistent pupillary membrane
• Progressive retinal degeneration
• Secondayr glaucoma

Welsh Springer Spaniel

• Hip dysplasia (infrequent)
• Hereditary cataract
• Hypothyroidism
• Primary glaucoma
• Spermatogenic arrest with azoospermia

Welsh Terrier

• Luxated lens / secondary glaucoma

West Highland White Terrier

• Atopic dermatitis
• Cardiomyopathy
• Cataracts
• Chronic hepatitis
• Cirrhosis of the liver
• Cleft palates
• Copper-associated hepatopathy
• Craniomandibular osteopathy
  • Irregular osseous proliferation of mandible and tympanic bulla
  • Discomfort from eating 
  • Intermittent fever up to 104 deg F
  • Begins at 4-7 months
  • Progresses to 11-13 months then may stop
• Deafness
• Degenerative valve disease
• Ectopic ureter
• Epidermal dysplasia
• Enlarged orbit
• Fatty liver syndrome
• Globoid cell leukodystrophy (Krabbe's disease)
  • Progressive signs beginning at 3-6 months old
  • Pelvic stiffness
  • Cerebellar disturbance
  • CSF total protein elevated
  • Enzyme deficiency with collections of globoid cells in the DNS
• Hip dysplasia
• Ichthyosis
• Inguinal hernia 
  • Defective formation of linea alba associated with protrusion of abdominal contents through inguinal canal
• Keratoconjunctivitis sicca
• Legg-Perthes disease
  • Avascular aseptic necrosis of femoral head
• Luxating patella
• Malasezia dermatitis
• Myotonia
• Pulmonic stenosis
• Pyruvate kinase deficiency
• Seborrhea, primary
• Tetralogy of Fallot
• Ventricular septal defect

Whippet

• Cryptorchidism
• Degenerative valve disease
• Demodectic mange
  • Communicable 
  • Due to demodex in hair follicles
• Idiopathic onychodystrophy
• Multiple Drug Sensitivity
  • Occurs in at least one line of Longhaired Whippets you can refer to the original article at:
  • http://www.pnas.org/cgi/reprint/101/32/11725
  • MDR1 gene
  • Problme drugs:  Ivermectin, Loperamide, Doxorubicin, Vincristine, Vinblastine, Cyclosporin, Digoxin, Acepromazine, Butorphanol
  • Potential Problem Drugs: Ondansetron, Domperidone, Paclitaxel, Mitoxantrone, Etoposide, Rifampicin, Quinidine, Morphine
  • Test available: http://www.vetmed.wsu.edu/depts-VCPL/test.asp
• Partial alopecia
  • Affects 2/3 of body including head, trunk (ventral) , dorsal pelvic region and proximal legs

Wirehaired Fox Terrier

• Color dilution alopecia
• Megaesophagus
• Tetralogy of fallot

Wirehaired Pointing Griffon

• Hip dysplasia
  • Deformed coxofemoral joints with clinical signs from none to hip lameness
  • Shallow acetabulum
  • Flattened femoral head
  • Subluxation 
  • Secondary joint disease

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X

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Y

Yorkshire Terrier

• Color dilution alopecia
• Degenerative valve disease
• Dermatophytosis
  • Microsporum canis
• Distichiasis
  • Two rows of eyelashes
  • Results in irritation and epiphora
• Fatty liver syndrome
• Hydrocephalus
• Hypoplasia of dens
  • Either hypoplasia of dens or its nonunion with C2 
  • Produces atlantoaxial subluxation
  • Onset about any age producing signs ranging from neck pain to quadriplegia
• Injection reactions
• Keratoconjunctivitis sicca
• Legg-Perthes disease
• Lymphangiectasia
• Melanoderma
• Patent ductus arteriosus
• Patellar luxation
  • Medial or lateral
  • Medial is more common
  • Tibial rotation on its long axis
  • bending of the distal end of the femoral shaft
  • Shallow femoral trochlea
  • Lameness at 4-6 months of age
• Portosystemic shunts
• Retinal dysplasia
• Tracheal alopecia

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Z

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Return to Dr. Bobs Animal Health Site

Cardiology Listings based upon "Manual of Canine and Feline Cardiology" fourth edition 2008, W.B. Saunders

by Larry P. Tilley, Francis W.K. Smith, Jr., Mark A. Oyama, and Meg M Sleepe